Monday, April 20, 2009

Phenol

Phenol, also known as carbolic acid, is a toxic, white crystalline solid with a sweet tarry odor, commonly referred to as a "hospital smell". Its chemical formula is C6H5OH and its structure is that of a hydroxyl group (-OH) bonded to a phenyl ring; it is thus an aromatic compound. It is also used in the production of drugs (it is the starting material in the industrial production of aspirin), herbicides, and synthetic resins (Bakelite, one of the first synthetic resins to be manufactured, is a polymer of phenol with formaldehyde).

Phenol has antiseptic properties, and was used by Sir Joseph Lister (1827-1912) in his pioneering technique of antiseptic surgery, though the skin irritation caused by continual exposure to phenol eventually led to the substitution of aseptic (germ-free) techniques in surgery. Lister decided that the wounds themselves had to be thoroughly cleaned. He then covered the wounds with a piece of "rag" or "lint" covered in carbolic acid. It is also the active ingredient in some oral analgesics such as Chloraseptic spray. Phenol was also the main ingredient of the Carbolic Smoke Ball, a device marketed in London in the 19th century as protecting the user against influenza and other ailments.

Phenol is also used in the preparation of cosmetics including sunscreens, hair dyes, and skin lightening preparations. Compounds containing phenol moieties can be used to prevent ultraviolet light-induced damage to hair and skin due to the UV-absorbing properties of the aromatic ring of the phenol.

It is also used in cosmetic surgery as an exfoliant, to remove layers of dead skin. It is also used in phenolization, a surgical procedure used to treat an ingrown nail, in which it is applied to the toe to prevent regrowth of nails. 5% Phenol is sometimes injected near a sensory nerve in order to temporarily (up to a year) stop it transmitting impulses in some intractable cases of chronic neuropathic pain.

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